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Last Updated on January 15, 2019

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Ciprofloxacin is a synthetic antimicrobial agent – it does not happen in nature. Many such drugs are for the most part still relatively young, but no less successful. For Ciprofloxacin, there are numerous areas of application because of its bakterienabtötenden effect. These include colon, biliary and urinary tract infections, as well as meningitis.

How Ciprofloxacin works

Like other antibiotics Ciprofloxacin blocked the growth of bacteria, by minimizing their ability to form new genetic material (DNA) and cell division. Because it inhibits several important enzymes for – the so-called DNA gyrase and some topoisomerases. These are enzymes that break down the genetic material temporarily in order to transfer them from the Super Helix in a relaxed form. This process is essential to establish that the information of the genetic information can be read – he is suppressed, is cells can not divide

The precise mechanism of action and other effects of Ciprofloxacin and other “gyrase inhibitors” are still being studied and are still being explored.

Ciprofloxacin is effective only against bacteria that proliferate. The higher the reproduction rate, the better the effect. It refers to those antibiotics therefore also known as “secondary bactericidal”.

When is Ciprofloxacin used?

Ciprofloxacin belongs to the fluoroquinolone group and exhibits a high activity against gram-negative bacteria. But it can also be used against gram-positive pathogens and against those who smuggle themselves into the body’s cells.

At present, there are numerous Ciprofloxacin applications. On the one hand affects the antibiotic against many infectious diseases such as bowel disease or biliary and abdominal infections, provided a more sensitive to Ciprofloxacin bacteria is responsible. Secondly, the active ingredient in urinary tract infections is used as a reserve antibiotic. This means that the result of severe side effects, especially in children and adolescents, will only be resorted to therapy with Ciprofloxacin when the disease very difficult runs and do not affect other therapies sufficient.

Also, anthrax and caused by Legionella pneumonia (CAP) can be treated with the drug. In classical pneumonia treatment with Ciprofloxacin, however, is less useful because it only weakly on the pathogen, pneumococcal bacteria, acts.

When family history of meningococcal meningitis (a form of bacterial meningitis) is Ciprofloxacin administered as a preventive measure to relatives in order to counteract the disease.

if a patient develops gonorrhea (“gonorrhea”) to, this disease can be treated once with Ciprofloxacin. This, however, has a subsequent insensitivity of the pathogen to the drug result.

How Ciprofloxacin is applied

The drug can be administered in various dosage forms. These are, as well as Ciprofloxacin dosage, highly dependent on the disease to be treated and the pathogen responsible for it.

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One common form of administration is peroral form. This means that the preparation is swallowed by the patient, mainly as a tablet. This must be done every day at about the same time, in order to always ensure a sufficient concentration of the drug in the body. To be taken with or without food; taken on an empty stomach, but the drug usually occurs faster through the bloodstream. It is important that the Ciprofloxacin tablets are not chewed while taking.

Other types of administration such as preparations for intravenous administration or eye and ear drops with the antibiotic are also available.

Ciprofloxacin-containing medicines are available in different dosage. When tablets are mostly to amounts of active compound of 250mg or 500mg per piece. The Ciprofloxacin preparation is normally applied or taken twice a day. But this case is strictly the instructions of the physician or pharmacist to follow.

What are the side effects of Ciprofloxacin?

Treatment with Ciprofloxacin may result in different frequency to undesired side effects. The meistbeobachteten include nausea, and rashes.

Also, the structure of tendons and tendon attachments can be obtained by the use of Ciprofloxacin change. This pain, swelling and cracks especially in the area of ​​the Achilles tendon may occur. For persons over 60 years the risk of impairment of the tendons by Ciprofloxacin increases.

The Ciprofloxacin can also cause disorders of the central nervous system. Among them are, for example, sensory disturbances, fatigue and hallucinations. These impairments occur but rarely.

What should be considered when taking Ciprofloxacin?

Antibiotics like Ciprofloxacin must be applied over the entire period prescribed by the doctor without interruption as other antibiotics. The intake must not be interrupted prematurely, even if the disease symptoms already disappear. This could lead to another outbreak of the disease, which is then even harder to treat because the body remaining pathogens can adapt to the drug. Experts speak of the development of resistance.

drugs and foods that contain a lot of multiply charged metal ions can form so-called complexes with Ciprofloxacin, which reduce the effectiveness of the drug. Therefore, for example, is to avoid the intake of dairy products for the duration of the treatment.

Ciprofloxacin should be administered either during pregnancy, nor during lactation, since it can be harmful harm the embryo or the baby. For the same reason the gift of children and adolescents during the growth period is recommended only under the supervision of a specialized doctor.

Since Ciprofloxacin lowers the seizure threshold in the brain, it is contraindicated in patients who suffer from seizures (), not be used. Impairment of responsiveness, particularly in traffic or operating machinery, are temporary side effects of treatment with Ciprofloxacin. Alcohol enhances these phenomena. Therefore, patients should be used during treatment on alcohol consumption renounce

Also, sunbathing or tanning beds should be avoided during the application period, since Ciprofloxacin makes the skin more sensitive to light.

How to obtain medicines containing the active ingredient Ciprofloxacin

Ciprofloxacin is only available on prescription and may be taken only after medical instructions. The prescribed drug is issued in pharmacies upon presentation of the prescription.

How long Ciprofloxacin is known?

The drug was developed in 1981 by the company Bayer and is thus a relatively young drug. Since expiration of the patent many supplements are in various dosage forms on the market. Typical dosage forms are Ciprofloxacin tablets, -Infusionslösungen and drops.

What you should also know about Ciprofloxacin

Antibiotics from the group of fluoro quinolines usually affect the efficacy of hormonal contraceptives. Has been shown in clinical trials that Ciprofloxacin does not impair the effectiveness of the contraceptive pill. As broke out at Oxford University a meningococcal meningitis, deshalbdie students were not treated with the standard drug rifampicin but with Ciprofloxacin.