Last Updated on March 16, 2024
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Levofloxacin
The active ingredient Levofloxacin is one of the most important means against bacterial diseases such as pneumonia, bladder infection and conjunctivitis. He is generally well tolerated, but can in rare cases lead to gastrointestinal complaints and fungal infections. Patients under 18 years, pregnant and lactating women may medicaments containing Levofloxacin, not take. Here you can read everything about Levofloxacin.
How Levofloxacin works
The human immune system protects the body from the implantation and spread of alien invaders. Once a pathogen finds its way into the body, the immune system responds instantly and combats this with different mechanisms. As a rule, the person never knows when the immune system is active, or there occur only minor discomfort as a result of the disease.
Sometimes, however, the body’s immune system does not make it immediately to combat the pathogen successfully. The symptoms are then more severe. Can the body not the pathogens are more Lord, medications can help the defensive struggle.
These drugs include the antibiotic Levofloxacin. It engages in the genetic material synthesis (DNA synthesis) of a bacteria so that the germs are killed. Thus, the immune system has to do is look after the elimination of the bacteria, and the symptoms of the disease improve very quickly.
Pharmacokinetics and metabolism of Levofloxacin
After taking over the mouth of the drug is almost completely absorbed from the intestine into the blood. After the distribution in the body Levofloxacin is excreted largely unchanged through the kidney.
When is Levofloxacin used?
Among the areas of application (indications) of Levofloxacin include:
- pneumonia
- acute bronchitis
- Complicated urinary tract infections (with the participation of the renal pelvis)
- skin diseases caused by bacteria
- , which was caused by bacteria
How Levofloxacin is used
The active ingredient Levofloxacin is applied in the form of tablets or eye drops, in very severe infections also by infusion (dose directly into the blood).
The dosage is taken orally (by mouth in the form of tablets) is usually between 250 and 500 milligrams daily. The duration of treatment, depending on the severity of the infection between seven and 28 days.
Eye drops containing Levofloxacin are four dropped daily in the affected eye to eight times. The duration of treatment depends here on the severity of the disease.
The amount of active ingredient when administered directly into the bloodstream (infusion) is usually determined individually.
Patients with renal impairment receive a reduced dosage.
What are the side effects of Levofloxacin?
Often, that is, at one to ten percent of those treated, causes Levofloxacin side effects such as gastrointestinal complaints.
Occasionally (in less than one percent of people) it comes after taking Levofloxacin to fungal diseases, weight loss, dizziness, depression and allergic reactions.
Even more rarely leads taking Levofloxacin to blood disorders, muscle and joint complaints and damage to the tendon (tendinopathy).
There are a few cases are known in which Levofloxacin has led to a certain heart rhythm disorder (QT prolongation).
If the active ingredient in the form of eye drops applied, usually occur only local side effects (such as allergic reactions or temporary impairment of vision).
What should I watch for while taking Levofloxacin?
Levofloxacin should be given only by combining strict medical benefit-risk assessment with other agents also affect the heart’s rhythm. Such agents are, for example, different drugs to control heart rhythm (antiarrhythmics) such as quinidine, procainamide, Amiodarone and dronedarone.
Contraindications
Patients with seizure disorders () or heart rhythm disorders (arrhythmias), pregnant women, nursing mothers and children under the age of 18 should not be treated with the active ingredient Levofloxacin.
Interaction
The concomitant use with iron supplements or remedies for heartburn (with aluminum or magnesium salts) affect the absorption and thus the effect of the antibiotic.
The effect of the following substances is increased by concomitant administration of Levofloxacin:
- ciclosporin (medicine to suppress your immune system)
- warfarin and phenprocoumon (blood thinners)
Driving and using machines
As a side effect, deterioration of responsiveness occur. Therefore, patients during treatment with Levofloxacin not drive or operate heavy machinery on the road.
Parental
medications with Levofloxacin may children and adolescents in the growth phase (younger than 18 years) not be given.
Pregnancy and lactation
The drug can attack the cartilage tissue, especially when the body is just growing. For this reason, the drug should not be used in pregnancy and lactation. Instead associated with penicillin, cephalosporins (such as cephalexin) and macrolides (eg, Erythromycin) better proven alternatives for treating bacterial diseases.
How to obtain medication with Levofloxacin
medications with Levofloxacin are available by prescription and is therefore only available with a prescription from a doctor in pharmacy.
Since when Levofloxacin is known?
Levofloxacin is a relatively young drug. It was developed from another drug to treat bacterial diseases, by this has been slightly modified in its chemical structure. As “fluoroquinolone” second-generation Levofloxacin is better tolerated and that with comparable effectiveness.
More interesting facts about Levofloxacin
medication with Levofloxacin increase the risk to get a sunburn. Therefore, especially during treatment: Apply High sunscreen and avoid sun exposure