Last Updated on March 16, 2024
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What is fluoxetine?
Fluoxetine Is one of the selective serotonin reuptake inhibitors (SSRIs), one of the most active groups for treating depression and other mental illnesses. Although it is one of the first representatives of this class of drugs, it is still frequently and successfully used.
It may take 2 to 3 weeks for fluoxetine to start helping
- Antidepressants, such as fluoxetine, can begin to work on depression within the first fourteen days of therapy, and the improvement lasts for the next few weeks.
- When stressed, antidepressants like fluoxetine may take a little longer to do their job. Stress does decrease, although many people's stress is temporarily increased at the beginning of therapy.
- See 'Fluoxetine can help correct the chemicals your mind desires' to learn why it takes some time for the benefits of fluoxetine to increase.
- Some unwanted effects of Fluoxetine tend to occur at the beginning of therapy, but go away after a couple of days, such as feelings of nausea (nausea or vomiting).
- To get the maximum effect, you should take fluoxetine daily and let it work for you.
- Your doctor may start you on a very low dose and then gradually increase it over two to four weeks until the full dose.
Many men and women take fluoxetine for at least 6 weeks
- You and your doctor should discuss how long you want to take fluoxetine.
- It may take a very long time for the effects to work for you, but hopefully it is worth sticking with it.
- Continue taking fluoxetine until you feel better, which may take a couple of months, and then continue taking fluoxetine for the next 6-12 weeks as recommended by your doctor. Then you need to continue taking fluoxetine for at least two decades after receiving it, if your illness has returned.
- It can help keep you healthy. There is a greater chance that your symptoms will return if you stop taking fluoxetine soon.
- If you have side effects you can't live with, talk to your doctor about other alternatives.
- Consult with your doctor if you want to prevent taking fluoxetine to make sure it’s not too early for prevention. If you additionally stop taking the medication, you may need to reduce the dose to reduce the chance of unwanted effects.
- If you have bipolar disorder, it is very likely that your doctor will advise you to stop taking fluoxetine sooner. This is because with bipolar disorder, there is a chance that your mood will become too high with long-term use of antidepressants.
How and when to take?
Take Fluoxetine. It does not cause stomach upset, so it can be taken with or without food.
Fluoxetine can be taken by you at any time daily. If you have trouble sleeping, it is better to take it in the morning.
How much to take?
The dose of Fluoxetine for adults is 20 mg per day. But you may be initiated by. Some people may need a lower dose of fluoxetine or take it in the following cases. Including in men and women, as well as liver complications.
The dose can be increased to 20 mg per day, although the fluoxetine dose for children is 10 mg per day.
What should I do if I forget to take it??
Don't worry if you forget to take a dose. Take a second dose the next day at your usual time. Never take two doses at the same time to make up for a forgotten one.
If you often forget to take your doses, setting an alarm clock to remind you of this. You can ask your pharmacist for advice on how to remember to take your medicine.
Imagine if I take too much?
Seek advice from your doctor right away. Overdosing can lead to potentially serious symptoms, such as:
- Vomiting
- vibe
- feeling of fatigue
- arousal
- heart problems
- lung problems
- cramps
How Fluoxetine Works?
Serotonin is a natural messenger compound (or "neurotransmitter"), which plays an important role in areas of the brain that control thinking and mood. … Medications such as Fluoxetine Are known as selective serotonin reuptake inhibitors (SSRIs) because they prevent dopamine from being reuptaken into nerve cells.
As an antidepressant, Fluoxetine interferes directly with brain metabolism. The brain transmits messengers, called neurotransmitters, signals between nerve cells: After a nerve cell spreads, the messenger binding sites (receptors) of a neighboring cell dock and thus transmit the signal. To stop the signal, messengers are resumed in the cell of origin. The exact causes of depression are not yet known. We know, however, that at least one cause of depressive disorders is a lack of the neurotransmitter serotonin, perhaps (the "happiness hormone"). This is where Fluoxetine's effects come into play: It prevents the reuptake of serotonin already distributed in the cell – so the messenger can have a longer lasting mood and depressing effect on target cells. Moreover, specific receptors that bind fluoxetine directly to the target cell have recently been shown to mediate the same effect that serotonin can have.
You may drink some alcohol while taking fluoxetine
- If you consume alcohol, you can continue to consume any alcoholic beverages while taking fluoxetine, but ideally you should be in moderation. Because fluoxetine can cause drowsiness as a side effect, it is likely that alcohol may cause you to be more drowsy than usual.
- However, daily use of alcohol can worsen symptoms of depression, and you'll not feel the benefits of the medication.
- Side effects may cause you to become tired or lose attention when you first start taking fluoxetine.
- It can be dangerous if you drive a car, use machinery, or do anything that requires a lot of attention.
- Therefore, for the first day or two, it is best to avoid drinking alcohol until you understand how the medication affects you personally, or until the effects have passed.
Do not drive or ride a bicycle until after you have started taking fluoxetine
- Taking fluoxetine can affect your concentration when doing activities such as driving, cycling, using cars, etc.д., that require a lot of attention.
- It may be best to avoid such things for the first couple of days, until you understand how it affects you, or until the effects go away.
- You need to make sure you are safe to drive.
- You can go and practice emergency stops in a safe place, or find a friend or relative to go together and see if they see a difference in your driving.
- Don't worry – most men and women drive like normal while taking fluoxetine.
Try not to take fluoxetine for the first time just before exams
- Taking fluoxetine may affect your concentration to do things that require a lot of attention, such as exams.
- You need to talk to your doctor about any future screenings if you’re starting to take fluoxetine.
- You can choose to take classes together to delay starting them until you’ve finished them. You may find that it is much better to start taking fluoxetine to improve motivation and mood if there is more than a month break in between, but.
- Don’t worry – most people get tested as usual while taking fluoxetine.
Fluoxetine makes it hard to concentrate
- Taking fluoxetine can affect your concentration as well as your ability to do anything that requires a lot of attention.
- After the first couple of times, you may see how it affects you personally, or the effects may get much better.
Fluoxetine is not a banned substance
- Fluoxetine is not a banned substance in the game.
- Taking fluoxetine may affect your concentration for activities such as cycling, competitive gymnastics, or anything else that requires a lot of attention.
- It may be best not to exercise for the first couple of days until you understand how it affects you, or until the effects get better.
- Don't worry – most people who take Fluoxetine do sports as usual.
Fluoxetine may affect your weight
- The disadvantage of fluoxetine may be not feeling as hungry as usual, which can lead to weight loss.
- It’s pretty hard to know how it will affect each person who chooses it.
- Talk to your doctor about it if it bothers you.
Fluoxetine can make you tired
- you may feel tired in the first few days of taking fluoxetine. Condition should improve after the first week or two.
- If you feel very sleepy and have been taking it for at least a month, you need to see your doctor and find out what else you can do.
Let your family and friends know that you are taking fluoxetine so that they can support you and help you guard against unwanted consequences
- Fluoxetine side effects can put strain on your friendships and relationships, especially in the first couple of days after you start taking it.
- You may experience anxiety, for example, or it may make you irritable.
- All of these side effects should go away after a few days.
- After a month, you should feel the superior effects of fluoxetine, which in itself should improve your bonds.
- It can be a really great idea to pick a fantastic buddy who will tell you about your medication when you start taking it. (Or – even better – take a buddy to the doctor with you before you start taking the medication!)
- You can learn about them from the drug's instructions or on this website.
- They may let you know if the medication changes your behavior or causes side effects (sometimes it's hard for us to notice it ourselves).
Fluoxetine can have side effects that can affect your sex life
The effects of fluoxetine can have a big impact on your life after a while because your mood increases and you also become more interested in relationships and life .
Possible side effects include:
- Men may have painful erections (but this is rare), or difficulty getting an erection and ejaculating.
- Men may have painful erections that last a very long time (priapism), you should also go to the hospital immediately for treatment
- Girls may experience vaginal bleeding
- Girls may not cum (reach orgasm) quite the way they used to
- Both people may experience some breast enlargement and milk leakage (but this is rare).
- You may have a decreased libido
- If you lose weight or get other side effects, you may just not feel as sexy as before
These effects should go away after the first two or three weeks. If they don't go away, see your doctor and see what else you can try.
Fluoxetine does not affect human fertility
Talk to your doctor if you are trying to get pregnant
- In animal tests, fluoxetine affected sperm quality, making men less likely to get pregnant (less fertile).
- SSRI drugs have had some effects on sperm quality in humans, which appear to be reversible if you stop taking the drug.
- However, there are reports of real fertility problems in people taking these drugs.
Should talk to your doctor about alternatives.
It's important to keep feeling good throughout your pregnancy Continuing to take fluoxetine should be considered in addition to the option of discontinuing. An alternative medication may also be considered. Please see below to learn more.
You need very good contraception when taking fluoxetine
- You need to use reliable contraception while taking fluoxetine. This is because there is a possibility of problems for your child if you take fluoxetine.
- If you become pregnant while taking fluoxetine, you should continue taking the drug and talk to your doctor as soon as possible to see if you need to change or stop taking it.
- Remember, you need to stay well throughout your pregnancy, and you may need a medication that allows you to do this.
Fluoxetine can cause heart problems in a growing baby, as well as other symptoms in newborn babies
Ladies taking fluoxetine should talk to their doctor about their alternatives. If you become pregnant while taking fluoxetine, you should discuss this with your doctor.
Your doctor can let you weigh your options. When taken during pregnancy, fluoxetine can sometimes cause difficulties in carrying a baby or a newborn baby (see. more below).
During pregnancy and thereafter, it is important to stay healthy, and for many women, it may be better to continue taking fluoxetine (or an alternative medication) during pregnancy and thereafter.
The BUMPS (Greatest Use of Medicines in Pregnancy) website has excellent information and advice on the safety of fluoxetine in pregnancy: https://medicinesinpregnancy.org/Medicine–pregnancy/Fluoxetine/
- There is a slightly higher chance of cardiovascular problems in the baby if you take fluoxetine in the early stages of pregnancy.
- If you and your doctor agree to continue taking fluoxetine throughout your pregnancy, you need to tell your midwife that you are taking it until you return.
- If fluoxetine is taken in the previous 3 weeks of pregnancy, it can cause a serious condition called persistent pulmonary hypertension of the newborn (PHHN). It looks a little blue and will make the baby breathe.
- PPHN occurs in the first 24 hours after you are admitted to the maternity hospital. You will need support from doctors and midwives, so it is best if they monitor your symptoms.
- Other unwanted effects may occur in the newborn, which may not appear immediately. So you should pay attention to them in the first few days after you have your baby: shivering, irritability, trouble sleeping
Fluoxetine can be passed on to the baby in breast milk
- Fluoxetine can be transmitted to an infant in breast milk, and there are side effects in breastfed infants.
- Remember that you need to stay well while you are interacting with and caring for your baby. Because of this, it may be better to take the medication while breastfeeding.
- You need to discuss this with your doctor. Alternatively, you can continue taking the minimum dose of fluoxetine or use another medication that appears almost never in breast milk.
- You may also want to consider bottle-feeding with formula if you have trouble breastfeeding while taking the medicine.
- The total amount of fluoxetine in breast milk is usually about 3 percent of the dose taken by the mother, but it may increase over time.
- Discuss with your doctor or midwife your choice of feeding.
- If you decide to continue taking fluoxetine, your doctor may prescribe a lower dose to reduce the chance of side effects from it.
- Taking fluoxetine only before your baby's longest nap can help reduce the total amount of fluoxetine transmitted to the baby through breast milk.
- Make sure your doctor, nurse, or health care provider checks your baby for any unwanted effects. These include: drowsiness, colic, feeding problems, poor weight gain.
- If there are any problems, your doctor may lower your dose of fluoxetine or switch to another drug.
- If your baby was born prematurely or has health problems, you may have to be very careful about taking medication while breastfeeding. Discuss this with your doctor.
- To learn more about breastfeeding while taking antidepressants, visit the Breastfeeding Network website: https://www.breastfeedingnetwork.org.uk/antidepressants/
High levels of caffeine from fluoxetine can cause serotonin syndrome
- Should you drink a lot of coffee, cola, or drinks with caffeine if this can cause you to have the syndrome.
- Indicators are some combination of the following symptoms – high stress, agitation, confusion, shivering, sweating, diarrhea (liquid feces), rapid heartbeat, or bizarre muscle movements
- You should go to the hospital immediately if you have any of these symptoms.
Fluoxetine can slow down body growth and sexual development in young people
- Fluoxetine has shown some effects of delayed development and delayed sexual development (puberty) in several children and young adults.
- Your doctor should evaluate your dilation when you take it.
- If this worries you, talk to your health care provider or pharmacist about it.
On a case-by-case basis, your doctor decides how long you should use Fluoxetine. However, drug therapy for depression with Fluoxetine has been shown to last at least six months. Obsessive-compulsive disorder is characterized by shorter periods of treatment.
What are the side effects of Fluoxetine?
Because the antidepressant has particularly long-lasting activity and persistence in the body, it requires special attention when treating side effects. Because the effects of Fluoxetine may continue for several more days after you stop taking the drug. More than one in ten patients treated with Fluoxetine experience weight loss, gastrointestinal distress (nausea, vomiting, chest pain). Male patients in particular should be warned about possible sexual dysfunction. With every tenth to hundredth patient, Fluoxetine can cause weight gain, hypertension, and visual disturbances. In addition, the heart rhythm may be altered: The so-called QT interval on the ECG may be increased, which should especially be considered if the patient continues to take additional medications In the event of a rash, shortness of breath and general symptoms of an allergic reaction, treatment should be stopped immediately and a doctor consulted, as it can lead to life-threatening symptoms, as with other allergies. Because of the drug's slow elimination rate, it may take a very long time for adverse drug reactions (ADRs) to subside.
Before taking Fluoxetine
If other centrally acting medications are taken in addition to Fluoxetine (t.е. acting in the brain), this should be discussed in advance with your doctor or pharmacist. This is especially true of other antidepressants (especially "MAOIs") and supplements that act directly on the serotonin system, such as tryptophan, tramadol, and migraine medications (triptans such as sumatriptan, which is also available without a prescription, are part). Combinations with Fluoxetine may "serotonin syndrome" Come to be called that require immediate medical attention. Fluoxetine's breakdown process involves enzymes in the liver that significantly degrade other active substances in the body. Therefore, when used concomitantly, possible interactions. This applies, for example, to sleeping pills and tranquilizers from the benzodiazepine group (such as diazepam), epilepsy medications (antiepileptic drugs such as phenytoin or carbamazepine), drugs to treat heart rhythm disorders (such as flecainide and encainide), drugs to treat high blood pressure (such as metoprolol), chemotherapy drugs (such as vinblastine) and other antidepressants or antipsychotic drugs. In addition, alcohol should be avoided during Fluoxetine therapy because of the added burden on the liver. Concurrent use of anticoagulants may lead to increased anticoagulation and increased risk of bleeding. Therefore, blood clotting rates should be closely monitored, especially at the beginning of therapy. The active ingredient, Fluoxetine should not be used in children and adolescents under 18 years of age. On the one hand, there is no data on the effects of therapy on child development. On the other hand, Fluoxetine has just shown in adolescents and young adults an increase in suicidal behavior that actually led to suicide by increasing the effects of Fluoxetine in some cases with suicide. This undesirable effect is common to almost all SSRIs. Pregnant and nursing mothers should not take Fluoxetine, as increased abnormalities in child development have been observed during treatment. If a woman becomes unplanned pregnant during treatment with Fluoxetine, the antidepressant should be stopped immediately and reported to your doctor.
Where to buy Fluoxetine online?
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Since when is Fluoxetine known?
As early as 1972, Fluoxetine was studied by the pharmaceutical company Eli Lilly, in 1977 it was submitted to the United States for approval. After years of research and evaluation, Fluoxetine was approved in the United States in 1987. The patent on Fluoxetine was terminated in 2001, allowing other generic Fluoxetine (generic drugs) to be brought to market at lower prices.
More interesting facts about Fluoxetine
Fluoxetine Was one of the first so-called "blockbuster drugs" – Drugs that make at least one billion dollars in U.S. dollars annually for their manufacturers. The Food and Drug Administration (FDA) approved fluoxetine, under the brand name Prozac, in December 1986 for the treatment of depression. From its introduction to the market in the late 1980s, Prozac ranked as the fifth largest selling pharmaceutical product in the United States. The active ingredient of Prozac, fluoxetine, differs from most of the other antidepressants in that it is a selective serotonin reuptake inhibitor (SSRI). However, unlike the tricyclic antidepressants and the monoamine oxidase inhibitors, fluoxetine was believed to be safer for its recipients. For some reason, perhaps because it is thought to produce fewer side effects than the tricyclic antidepressants, a general population began to equate the selective serotonin reuptake inhibitor with "antidepressant." Since the 1970s there has been much public debate over the dangers of antidepressant use and especially over the side effects of tricyclic antidepressants. This debate seems to be especially focused on the side effects of tricyclic antidepressants and their potential links with the deaths of some users. The more frightening images of the potentially fatal side effects of antidepressants as promoted by critics has perhaps contributed to the reluctance of the general population to seek treatment for depression. The Prozac scandal is a prime example of the potential for and the occurrence of the use of pharmaceuticals to enhance market share. The initial success of fluoxetine, which was a new and exciting drug when it hit the market in the late 1980s, provided market research for other antidepressants. As a result of this increased interest in depression and antidepressant use, pharmaceutical companies now market more than thirty antidepressants, as well as hundreds of drugs and medical devices that may be used to treat depression. The Prozac controversy continues to be a major one. The FDA has been accused of overseeing an inadequate drug approval process for the antidepressant. In addition, some individuals and families have accused the FDA of failing to adequately inform patients about the possible side effects of the drugs. The FDA has been the target of protests and demonstrations by patients, drug rehabilitation professionals, and patients' families. On occasion, a few protestors have been hospitalized for "threatening" their physicians. In October 1987, the United States Senate Public Health Committee, chaired by Senator Edward Kennedy, conducted hearings to investigate the approval of the drug. The committee reviewed a report by Dr. Herbert Pardes of the FDA. This report included the results of a survey conducted by the National Institute of Mental Health (NIMH). The NIMH survey found that only 23 percent of the respondents who took Prozac indicated that they "got better" with the drug. Other side effects of Prozac included nausea, insomnia, headaches, agitation, seizures, vertigo, fatigue, memory loss, nervousness, irritability, and insomnia. In some cases, patients reported that their problems were so severe that they felt compelled to stop taking the drug. The FDA required Eli Lilly to run more research studies on the side effects of Prozac before it could be sold. After this research showed that there was little cause for concern about the side effects of the drug, the FDA in January 1988 approved the drug for the general public to use without prior clinical trials. In March 1990, a number of articles in major newspapers appeared revealing that Prozac, Zoloft, and Paxil were now found to have "unexpected side effects" in children as young as four years old. Reports of depression and other negative side effects prompted researchers to conduct additional studies on fluoxetine. In November 1990, the New England Journal of Medicine published an article reporting that a six-week study of fluoxetine in eleven children showed that the drug produced memory loss in some of the children. The researchers suggested that this loss of memory could be related to fluoxetine's potential to alter nerve cells in the brain.