Last Updated on March 16, 2024

Most online pharmacies offer Propafenone 150 mg. In case you prefer to get Propafenone online, first read recommendations on buying drugs online.

Propafenone is a medicine that is often prescribed for patients with arrhythmia, or irregular heartbeat. It works by regulating the heartbeat and stabilising the electrical signals in the heart. Although propafenone is a prescription medicine, it is available without a prescription in some countries. However, it is important to note that in the UK propafenone is only available on prescription and cannot be bought over the counter.

If you are looking for propafenone for your own use, it is important to talk to your doctor about your options. Your doctor will be able to determine if propafenone is the right medication for you and will be able to write you a prescription if necessary. It is not recommended that you buy propafenone over the counter without first consulting a health care professional, as improper use of the medication can lead to serious health complications.

In conclusion, while it may be possible to buy propafenone over the counter in some countries, it is not available without a prescription in the UK. It is important to consult a doctor before using propafenone to ensure that it is used safely and effectively for your individual needs.

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What is Propafenone?

Propafenone is used to treat cardiac arrhythmias. The human heart works hard every day, beating an average of 60 to 80 times a minute to pump blood and carry vital oxygen to the farthest corners of the body. This pumping power must all work together to reach the heart’s muscle fibres with precision. Muscle activity is controlled by its own energy system: The sinus node, a natural pacemaker, produces regular electrical signals. This current travels along fixed pathways throughout the heart, causing the muscles to work. When the signal reaches the muscle, it contracts – the current signal acts as a clock for the heartbeat. Cardiac arrhythmias are changes in the electrical system of signal generation or signal conduction: the heartbeat is too fast or too slow, there are missed heartbeats or extra beats. Not all arrhythmias are dangerous and require treatment. But if the disturbance is severe, the heart’s ability to pump blood decreases. This can lead to symptoms such as tiredness, anxiety or even loss of consciousness. In extreme cases, the heart may stop pumping blood, leading to acute heart failure, also known as sudden cardiac death.

Antiarrhythmics are medicines that control the heart rhythm. They work by changing the electrical signal and its path through the heart muscle. In this way, they prevent disturbances in the heart’s electrical system. The current system is so sensitive that eliminating disturbances in one place can trigger new arrhythmias elsewhere: Many of these drugs can themselves cause new arrhythmias. Propafenone is a class 1c antiarrhythmic. It is used to treat arrhythmias associated with a fast heartbeat. Propafenone works by slowing down the rate at which the signal travels through the heart muscle. This allows fewer electrical signals to travel through the heart muscle per minute – the heart rate decreases.

Propafenone is used to treat rapid heartbeats that originate in the atrium of the heart or in the AV node, the junction between the atrium and the ventricle. If the arrhythmia originates directly from the ventricle, propafenone should only be used if the situation is life-threatening.

Pharmaceutical Forms

Propafenone is available in the following pharmaceutical forms:

• Tablets: Immediate-release and extended-release formulations
• Capsules: Sustained-release formulations

Dosages

The dosage of Propafenone varies depending on the patient’s condition and the specific formulation used. Typical dosages include:

• Immediate-release tablets: 150 mg to 300 mg every 8 hours
• Extended-release tablets: 225 mg to 425 mg every 12 hours
• Sustained-release capsules: 225 mg to 325 mg every 8 to 12 hours

How to Take

Propafenone tablets or capsules should be taken orally with or without food, as directed by a healthcare provider. It is essential to adhere to the prescribed dosage regimen and not to exceed recommended doses.

Side Effects

Common side effects of Propafenone may include:

• Dizziness
• Fatigue
• Nausea
• Constipation
• Visual disturbances

Severe side effects such as proarrhythmia and exacerbation of heart failure may occur rarely.

Interaction with Other Medicines

Propafenone may interact with certain medications, including:

• Beta-blockers
• Calcium channel blockers
• Digoxin
• Amiodarone
• Warfarin

Interaction with Alcohol

Combining Propafenone with alcohol may potentiate central nervous system depression and increase the risk of adverse effects. Patients should exercise caution and limit alcohol consumption while taking this medication.

Contraindications

Propafenone is contraindicated in individuals with:

• Hypersensitivity to the drug
• Severe bradycardia
• Second- or third-degree atrioventricular block
• Sick sinus syndrome
• Cardiogenic shock

History of Drug Discovery

The discovery of Propafenone marked a significant advancement in antiarrhythmic therapy, offering clinicians a novel agent with potent and selective actions on cardiac ion channels. Since its introduction, Propafenone has become an integral part of the armamentarium for treating cardiac arrhythmias.

• Propafenone was first synthesized in the 1960s and introduced for medical use in the 1970s.
• It is classified as a Class IC antiarrhythmic agent according to the Vaughan Williams classification.
• Propafenone’s efficacy in suppressing arrhythmias has made it a cornerstone therapy in the management of certain cardiac rhythm disorders.