Mixing alcohol and spironolactone can be dangerous and can lead to various side effects, including feeling sleepy, dizzy, having low blood pressure, and becoming dehydrated. It can also harm your liver or interfere with its functioning. Therefore, it is important to seek the advice of your healthcare provider to discuss whether or not you should consume alcohol while taking spironolactone. The liver is the organ that can be most at risk in this situation.

It's recommended that you avoid alcohol consumption before and during the time you're taking spironolactone. The amount of time you should wait without drinking alcohol before taking spironolactone may vary.

It is not recommended to consume alcohol the night before taking spironolactone. Alcohol can increase the risk of side effects such as dizziness, drowsiness, and dehydration. It is important to follow the instructions provided by your healthcare provider and to avoid alcohol while taking spironolactone.

It is recommended to avoid consuming alcohol while taking spironolactone. Alcohol can increase the risk of side effects and may also reduce the effectiveness of the medication. Therefore, it is advised to wait until you have finished your course of spironolactone before drinking alcohol.

The elimination rate of spironolactone from the body is approximately 90% within 24 hours.